Determination of antibiotic resistance rates of Escherichia coli and Klebsiella pneumoniae isolates, which are the causative agents of urinary tract infection in pregnant women

Aim: Urinary tract infections are common during pregnancy. Infections seen pregnancy have a spectrum ranging from asymptomatic bacteriuria to cystitis, pyelonephritis and, urosepsis. In this study, it was aimed determine the antibiotic resistance rates of Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) isolates isolated urinary cultures pregnant women who applied Ankara Training Research Hospital. 
 Material Method: The identification susceptibility E. K. samples Hospital between January 2021 December 2022 were investigated with VITEK-2 (Biomerioux, France) fully automated system, presence extended-spectrum beta-lactamase (ESBL) by combined disc diffusion method. obtained data analysed retrospectively.
 Results: Bacterial growth detected in 1090 (1.2%) out total 8923 urine over two-year period. 480 (4.4%) microbial agents reproducing culture 105 (0.96%) pneumoniae. rate strains 16.04% (77/480), ESBL 20.9% (22/105). Resistance amoxicillin-clavulanic acid, ceftriaxone, phosphomycin, ciprofloxacin, piperacillin-tazobactam, nitrofurantoin, imipenem, meropenem, ertapenem negative 15.9%, 8.82%, 20%, 11.1%, 5.88%, 0%, 0% respectively. positive determined as 66.5%, 100%, 2.2%, 33.8%, 11.5%, 53%, 12.5%, 28.5%, 3.5%, 4.5%, 62.5%, 35%, 22.7%, respectively.
 Conclusion: According our hospital, phosphomycin or carbapenems may be preferred due low empirical treatment coli-related women. pneumoniae, piperacillin-tazobactam rates.